ADVANTAGES
Avoids complications associated with artificial airways
Provides flexibility in initiating and removing mechanical ventilation
Reduces requirements for heavy sedation
Preserves airway defense, speech, and swallowing mechanisms
Reduces need for invasive monitoring
 
DISADVANTAGES
Can cause gastric distention, skin pressure lesions, facial pain, dry nose, eye irritation, discomfort, claustrophobia, and poor sleep, and mask leaks can occur
Circumstances in Which Noninvasive Positive Pressure Ventilation Should Be Changed to Invasive Ventilation
Respiratory arrest
Respiratory rate >35 breaths/min
Severe dyspnea with use of accessory muscles and possibly paradoxical breathing
Life-threatening hypoxemia: Pa02 <40 mm Hg or Pa02/F I 02 <200
Severe acidosis (pH <7.25) and hypercapnia (PaC02 >60 mm Hg)
Somnolence, impaired mental status
Cardiovascular complications (hypotension, shock, heart failure)
Failure of noninvasive positive pressure ventilation
Other circumstances (e.g., metabolic abnormalities, sepsis, pneumonia, pulmonary embolism, barotrauma, massive pleural effusion)